East and Central African Journal of Surgery
Association of Surgeons of East Africa and College of Surgeons of East Central and Southern Africa
Vol. 21, No. 1, 2016, pp. 170-176
Bioline Code: js16020
Full paper language: English
Document type: Research Article
Document available free of charge
East and Central African Journal of Surgery, Vol. 21, No. 1, 2016, pp. 170-176
© Copyright 2016 - Journal of Applied Sciences and Environmental Management
Analgesia in Patients with or without Single-shot Lamina Thoracic Paravertebral Block Following Breast Cancer Surgery in a Nigerian Hospital|
Rukewe, A; Ademola, A F; Fatiregun, A A & Ugheoke, A
Background: In this pilot study, we evaluated the postoperative analgesic effect of
the new lamina thoracic paravertebral block using a single-shot technique for
major breast cancer surgery.
Methods: A retrospective observational design was used to compare data involving
16 consecutive ASA 1 and 2 female patients who had unilateral modified radical
mastectomy with axillary clearance under general anaesthesia with paravertebral
block and 15 others without block between 13/03/2014 to 12/05/2015. We
compared the time to the first request for analgesic, total analgesic (opioid and
non-opioid) consumption (in mg) and postoperative pain scores over 72 h between
the two groups.
Results: One patient was excluded from the cohort due to block failure. The median
time to first request for analgesic was 43 h (25.2-73.0 h) in the block group versus 2
h (1.0-2.5 h), p=0001. The pain scores was significantly lower at all measurement
points among the block patients compared with the no-block group until 24 h
postoperatively. No patient in the block group required analgesic within 24 h after
surgery. The total consumption of pentazocine was nil (block group) vs. 154.0±74.2
(range 90-300) mg, p=0.0000001.
Conclusions: Single-shot lamina paravertebral block provided prolonged
postoperative analgesia and reduced opioid and non-opioid consumption.