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East African Journal of Public Health
East African Public Health Association
ISSN: 0856-8960
Vol. 5, No. 3, 2008, pp. 211-214
Bioline Code: lp08039
Full paper language: English
Document type: Research Article
Document available free of charge

East African Journal of Public Health, Vol. 5, No. 3, 2008, pp. 211-214

 en Seroprevalence of Toxoplasma gondii in Nazaret Town, Ethiopia
Negash, T.; Tilahun, G. & Medhin, G.


Objective: To determine the seroprevalence of toxoplasmosis, assess its zoonotic importance and identify factors associated with seroprevalence.
Methods: Questionnaire survey was conducted on 65 serum samples collected from male and female urban and peri-urban residents aged between 15 days and 65 years. Main outcome measures were feeding habits, purpose of keeping cats and association with family members. Serologic evidence of toxoplasmosis was conducted by the Modified Direct Agglutination Test (MDA T) and determination of HIV status using the HIV - Spot Test.
Results: Over 50% of the interviewed people had a history of consumption of raw or undercooked mutton and had close contact with cats. 60% of the serum samples analyzed by the MDA T had serologic evidence of Toxoplasma infection. Significantly higher MDA T tiers were encountered both in pregnant and immunocompromised individuals. The risk factors associated to Toxoplasma infection, i.e. raw or undercooked mutton consumption and presence of cats appeared significant.
Conclusion and recommendations: The significance of toxoplasmosis as a disease of zoonotic importance was demonstrated. Close contact between family members and the consumption of raw or undercooked mutton were the major risk factors in the transmission of the disease. Considering the relatively high prevalence as revealed by this study it would be important to conduct studies on a wider scale. It would also be important to increase public awareness and upgrade the knowledge on congenital toxoplasmosis.

Seroprevalence, Toxoplasma gondii, Nazareth Town, Ethiopia.

© Copyright 2008 - East African Journal of Public Heath

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