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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857
EISSN: 0255-0857
Vol. 23, No. 2, 2005, pp. 95-101
Bioline Code: mb05026
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Medical Microbiology, Vol. 23, No. 2, 2005, pp. 95-101

 en Epidemiological, Clinical and Prognostic Profile of Acute Bacterial Meningitis among Children in Alexandria, Egypt
Farag H.F.M., Abdel-Fattah M.M., Youssri A.M.


Purpose: To address the epidemiological characteristics and clinical indices that may predict the prognostic profile of meningitis among children.
Methods: Children admitted to Alexandria fever hospital with clinical diagnosis of meningitis/meningoencephalitis during the period 2002-2003 were recruited for the study. They were subjected to clinical examination as well as CSF bacteriological and serological investigations
Results: Three hundred and ten patients (195 males and 115 females) were included. About 65.2% of them were infected with acute bacterial meningitis (ABM) and 34.8% were infected with aseptic meningitis. In this study, ABM was caused by Haemophilus influenzae check for this species in other resources (21%), Streptococcus pneumoniae check for this species in other resources (13.9%), Neisseria meningitidis check for this species in other resources (14.2%) and other undetermined bacteria (16.1%). ABM showed significant association with age group 1-9 years (66.3%), low socio-economic class (96%), working mother (83.2%), more than two smokers in the family (62.9%) and cold seasons(fall 35.1% and winter 48.5%). Aseptic meningitis showed significant association with age group 3-15 months (100%) and previous immunization(81.5%). The overall case fatality rate was 10.3%; 13.9% for ABM and 3.4% for aseptic meningitis. 7.1% of all survivors developed epileptic attacks. Predictors for death or epilepsy events were high WHO meningitis score (≥ 9), decreased CSF glucose level (<10 mg/dL), more smokers in the family, generalised seizures, infancy (<1year of age) and working mothers.
Conclusion: This study highlights the importance of several predictors of the outcome of meningitis in children. It is concluded that quick and simple scoring scales, such as the WHO scale, are not only applicable but valuable prognostic tools for meningitis in children.

Meningitis, children, Egypt, risk factors, survival

© Copyright 2005 Indian Journal of Medical Microbiology.
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