Ecthyma gangrenosum is a rare and invasive cutaneous infection caused by
Pseudomonas aeruginosa
in the majority of cases, typically affecting immunocompromised patients, particularly those with neutropenia. We report a rare case of ecthyma gangrenosum in the absence of bacteraemia presenting as a solitary necrotic ulcer in a female patient with acute lymphoblastic leukaemia. A culture from the ecthyma lesion revealed the presence of
Pseudomonas aeruginosa
, but the results of repeated blood cultures were negative. The patient responded well to amikacin to which the isolate was susceptible
in vitro . Considering high rate of mortality, early diagnosis and prompt effective treatment is mandatory.