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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857 EISSN: 0255-0857
Vol. 25, No. 2, 2007, pp. 146-149
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Bioline Code: mb07041
Full paper language: English
Document type: Research Article
Document available free of charge
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Indian Journal of Medical Microbiology, Vol. 25, No. 2, 2007, pp. 146-149
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Brief Communication - Prevalence of central nervous system cryptococcosis in human immunodeficiency virus reactive hospitalized patients
Lakshmi, V; Sudha, T; Teja, VD & Umabala, P
Abstract
Central nervous system cryptococcosis is an important cause of mortality among human immunodeficiency virus (HIV) reactive patients. A retrospective study was conducted on a total of 1,863 HIV reactive hospitalized patients suspected of cryptococcal meningitis. Three hundred and fifty-nine cerebrospinal fluid specimens of these cases were screened for various cryptococcal investigations. Thirty-nine out of 359 (10.86%) showed a definite diagnosis of cryptococcosis with a mortality rate of 25.64%. Prevalence of cryptococcal meningitis in the total HIV reactive cohort was 2.09%. Concurrent cryptococcal meningitis and tuberculosis was seen in 33.3% cases. A high index of clinical suspicion and routine mycological surveillance is required to help an early diagnosis and appropriate therapy, as majority of patients respond well to therapy if treated early.
Keywords
Cryptococcal meningitis, CD4 cell counts, latex antigen test
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© Copyright 2007 Indian Journal of Medical Microbiology. Alternative site location: http://www.ijmm.org
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