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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857
EISSN: 0255-0857
Vol. 26, No. 2, 2008, pp. 117-122
Bioline Code: mb08036
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Medical Microbiology, Vol. 26, No. 2, 2008, pp. 117-122

 en Evaluation of the effectiveness of peracetic acid in the sterilization of dental equipment
Ceretta, R; Paula, MMS; Angioletto, Ev; Méier, MM; Mitellstädt, FG; Pich, CT; Junior, SA & Angioletto, E

Abstract

Purpose: To evaluate the effectiveness of peracetic acid in the microbiological sterilisation of dental materials.
Methods: Peracetic acid solution was evaluated at concentrations of 800, 1500 and 2500 ppm. At these concentrations, it was determined whether peracetic acid caused corrosion to dental instruments and induced cellular mutagenicity and cytotoxicidity. In addition, the minimum inhibitory concentration (MIC), the minimum bactericidal concentration (MBC), agar diffusion and diffusion by well method, were also verified.
Results: The corrosion rate, calculated from potentiodynamic assays was 10 -6 cm/year, indicating that the product does not damage equipment. The sterilisation capacity of peracetic acid at 2500 ppm was the best. The comet assay indicated genotoxic activity at 2500 ppm.
Conclusions: This study demonstrated the effectiveness of peracetic acid for sterilizing dental equipment, providing another alternative for the prevention of infections in clinics.

Keywords
Cytotoxicity, chemical agents, genotoxic activity, peracetic acid, sterilisation

 
© Copyright 2008 Indian Journal of Medical Microbiology.
Alternative site location: http://www.ijmm.org

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