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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857
EISSN: 1998-3646
Vol. 26, No. 4, 2008, pp. 349-351
Bioline Code: mb08107
Full paper language: English
Document type: Short Communication
Document available free of charge

Indian Journal of Medical Microbiology, Vol. 26, No. 4, 2008, pp. 349-351

 en Study of metallo-β-lactamase production in clinical isolates of Pseudomonas aeruginosa check for this species in other resources
Agrawal, G; Lodhi, RB; Kamalakar, UP; Khadse, RK & Jalgaonkar, SV

Abstract

A study of metallo-β-lactamase (MBL) production was done in clinical isolates of Pseudomonas aeruginosa check for this species in other resources . Isolates resistant to ceftazidime and imipenem were screened for MBL production by double disc synergy test (DDST) and minimum inhibitory concentration reduction test. There was complete correlation between two methods for imipenem. For ceftazidime, there was correlation between the two methods in all except four strains. In the screening test for MBL, ceftazidime - EDTA combination was better than imipenem - EDTA combination. 8.05% strains were MBL producers. Presence of MBL producer P. aeruginosa is a cause of concern. Simple DDST can be helpful for monitoring of these emerging resistant determinants.

Keywords
Metallo-β-lactamase, Pseudomonas aeruginosa, ceftazidime, imipenem

 
© Copyright 2008 Indian Journal of Medical Microbiology.
Alternative site location: http://www.ijmm.org

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