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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857
EISSN: 0255-0857
Vol. 28, No. 2, 2010, pp. 155-157
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Bioline Code: mb10045
Full paper language: English
Document type: Short Communication
Document available free of charge
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Indian Journal of Medical Microbiology, Vol. 28, No. 2, 2010, pp. 155-157
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Infection with hepatitis C virus genotype 3 - Experience of a tertiary health care centre in south India
David, J.; Rajasekar, A.; Daniel, H.D.D.; Ngui, S.L.; Ramakrishna, B.; Zachariah, U.G.; Eapen, C.E. & Abraham, P.
Abstract
To analyse the response rate and the predictive values of virological, biochemical and histological factors on HCV antiviral therapy in HCV genotype 3 infected patients, we retrospectively studied 21 HCV genotype 3 infected patients, who underwent HCV antiviral therapy. Low (57%) sustained viral response (SVR) rate and significant association of SVR with normalization of alanine transaminase (ALT) levels were observed in our study. Absence of early viral response (EVR) showed high (80%) predictive value on SVR. Absence of EVR and normalisation of the ALT levels can predict the outcome of HCV antiviral therapy.
Keywords
Early viral response, pegylated interferon, ribavirin, standard interferon, sustained viral response
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© Copyright 2010 Indian Journal of Medical Microbiology.
Alternative site location: http://www.ijmm.org
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