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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857
EISSN: 0255-0857
Vol. 29, No. 1, 2011, pp. 60-62
Bioline Code: mb11014
Full paper language: English
Document type: Case Report
Document available free of charge

Indian Journal of Medical Microbiology, Vol. 29, No. 1, 2011, pp. 60-62

 en Sepsis due to linezolid resistant Staphylococcus cohnii check for this species in other resources and Staphylococcus kloosii check for this species in other resources : First reports of linezolid resistance in coagulase negative staphylococci from India
Peer, M.A.; Nasir, R.A.; Kakru, D.K.; Fomda, B.A.; Bashir, G. & Sheikh, I.A.


Linezolid, a viable alternative to vancomycin against methicillin resistant staphylococcal isolates, has been in use for a decade around the globe. However, resistance against staphylococci remains extremely rare and unreported from most of the Asian countries. Herein, we report two cases of linezolid resistant, coagulase negative staphylococcal sepsis for the first time from India. The first case was an 18-year-old burn patient, who, after a major graft surgery, landed in sepsis, and linezolid resistant Staphylococcus cohnii with an minimum inhibitory concentration (MIC) of >256 μg/ml by both broth microdilution and Etest, was isolated from multiple blood cultures. The second patient was a 60-year-old male with an intracranial bleed and sepsis, from whose blood cultures, linezolid resistant Staphylococcus kloosii was repeatedly isolated. Linezolid MIC was >32 μg/ml by broth microdilution and >16 μg/ml by Etest.

Linezolid resistance, Staphylococcus cohnii, Staphylococcus kloosii

© Copyright 2011 Indian Journal of Medical Microbiology.
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