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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857
EISSN: 0255-0857
Vol. 29, No. 2, 2011, pp. 124-129
Bioline Code: mb11030
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Medical Microbiology, Vol. 29, No. 2, 2011, pp. 124-129

 en Evaluation of the therapeutic use of antibiotics in Aegean Region hospitals of Turkey: A multicentric study
Ozgenç, O.; Genç, V. E.; Ari, A. A.; Sibel, El; Saçar, S.; Ozunlu, H.; Akgul, A.; Demirturk, N.; Çetin, C.B.; Sungur, M.; Coskuner, S. A.; Avci, Meltem; Ergonul, O & , Antibiotic Resistance Study Group of Turkish Association of Clinical Microbiology and Infectious Diseases

Abstract

Purpose: The antibiotic restriction policy has been validated nationwide since February 2003 by the Ministry of Health because the excessive consumption of antimicrobials causes a high cost. The aim of this study was to evaluate the therapeutic use of antibiotics in Aegean Region hospitals and to assess the impact of this nationwide antibiotic restriction policy. This new policy is based on justification that the infectious disease (ID) physicians should be primarily responsible for the prescription of antimicrobials.
Materials and Methods: Eight university and government hospitals were included in the study. The criteria of the Council for Appropriate and Rational Antibiotic Therapy (CARAT) were considered. Both patient-based and antibiotic-based analyses were performed. For the analysis of inappropriate use, logistic regression was modeled.
Results: Therapeutic use was determined in 540 patients by a total of 29 ID physicians.In the study, 30.2% of the patients were given antimicrobials and empirically started antibiotics accounted for 79% cases of therapeutic antibiotic use, and 60% of those were inappropriate (P = 0.001). The appropriate use of ID level antibiotics (P = 0.000) were very compatible with other antimicrobial groups.
Conclusion: The study shows that the Turkish government′s new intervention policy on antimicrobial prescribing has been effective.

Keywords
Antibiotic restriction policy, appropriate antibiotic usage

 
© Copyright 2011 Indian Journal of Medical Microbiology.
Alternative site location: http://www.ijmm.org

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