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African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 3, No. 3, 2000, pp. 161-165
Bioline Code: md00046
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 3, No. 3, 2000, pp. 161-165

 en PHYTOCHEMICAL AND ANTIMICROBIAL STUDIES OF GYNANDROPSIS GYNANDRA AND BUCHHOLZIA CORIACEAE EXTRACTS
AJAIYEOBA, E. O.

Abstract

Extracts of leaves and stems of Gynandropsis gynandra check for this species in other resources L. (Briq.) and Buchholzia coriaceae check for this species in other resources Engl. (A. Chev.) were screened phytochemically for the presence of secondary metabolites and for in vitro antibacterial and antifungal properties respectively. The main secondary metabolites indicated in both plants were alkaloids, cyanogenetic glycosides and steroidal nuclues. Anthraquinones were slightly indicated. Hexane and methanolic extracts of each of the plant materials of the two plants were screened for antimicrobial properties using eleven clinical strains of human pathogenic microorganisms. At a concentration of 200mg/ml, the extracts displayed various degrees of activity in both bioassays. Of the eight extracts investigated, B. coriaceae stem hexane extract displayed the highest activities in both assays in the agar cup diffussion technique. The microorganisms that were used included six bacteria and five fungi. Ampicillin and tioconazole were used as standard reference drugs while methanol was incuded as a solubilising agent as well as a negative control in the study. Diameters of zones of inhibition were in the range of 10-24mm for the extracts and drugs.

Keywords
Buchholzia coriaceae, Gynandropsis gynandra, Phytochemical, Antibacterial, Antifungal

 
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