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African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 4, No. 3, 2001, pp. 143-145
Bioline Code: md01069
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 4, No. 3, 2001, pp. 143-145

 en LIPOLYTIC EFFECT OF Calotropis procera check for this species in other resources IN THE SKIN OF WISTAR RATS
AKINLOYE A.K, ABATAN M.O, ONWUKA S.K, ALAKA O.O & OKE B.O

Abstract

Histopathological studies of skin samples from Wistar rats treated once daily for four weeks with 20mg/gm body weight of the fresh leaf extract of Calotropis procera check for this species in other resources by the oral route showed significant degeneration of adipose tissue in the hypodermis and partial degeneration of the dermis at the site of merging with the hypodermis. No significant histological changes were, however, observed in the stratified squamous epithelium of the epidermis. Hair follicles and sebaceous glands were not affected. It was concluded from these observations that the subcutaneous layer was the one mainly affected by the treatment with the leaf extract.

Keywords
Calotropis procera, lipolysis, skin, rat

 
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