search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 7, No. 2, 2004, pp. 75-78
Bioline Code: md04017
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 7, No. 2, 2004, pp. 75-78

 en NEUROPHARMACOLOGICAL ACTIVITIES OF FICUS PLATYPHYLLA STEM BARK IN MICE
WAKEEL O.K, P.I AZIBA, ASHOROBI R.B, UMUKORO, S, ADERIBIGBE A.0 AND AWE E.O

Abstract

Methanol Extract Ficus platyphylla check for this species in other resources stem bark in dosages (17, 40 and 75, 150mg/kg) was found to produce a profound decrease in exploratory activity in mice, the extract indicated peripheral and central analgesic effects as shown by significant inhibition of acetic acid - induced writhing, and delayed onset in leptazol induced-convulsion (seizures) in mice respectively. It also decreases the rate of leptazol induced mortality in mice. The totality of these effects showed that the extract possesses depressant action on the central nervous system.

Keywords
Neuropharmacology, Ficus platyphylla, stem bark, mice

 
© Copyright 2004 - Ibadan Biomedical Communications Group

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2017, Site last up-dated on 16-Oct-2017.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil