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African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 7, No. 2, 2004, pp. 85-87
Bioline Code: md04019
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 7, No. 2, 2004, pp. 85-87

 en ANTI-INFECTIVE AND WOUND HEALING PROPERTIES OF FLABELLARIA PANICULATA
ABO A, OLUGBUYIRO J.A.O. AND FAMAKINDE S.A.

Abstract

The methanol leaf extract of Flabellaria paniculala check for this species in other resources was studied for its potency on normal wounds and infected wounds in rats. Wounds were inflicted on Wistar rats using excision model. Local infection was introduced into rat abdominal wounds using a 108 bacteria/ml inoculum. Two groups of infection were used: Staphylococcus aureus check for this species in other resources Pseudomonas aeruginosa check for this species in other resources . Rate of wound healing was assessed by contraction and p of epithelisation. Crude extract of F. paniculala demonstrated sic wound contraction and decrease in epithelisation period (p <0.05). On day 14, extract achieved 100% wound contraction in non-infected and Staphylococcus aureus while 100% wound contraction was recorded in Pseudomonas aeruginosa group on day 18. This drug is anti-infective as well as wound healing agent thus justifying the local uses of the plant for the treatment of skin diseases and sores.

Keywords
Flabellaria paniculala, infected wounds, wound contraction, wound healing

 
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