Methanolic extracts of five Nigerian mushrooms -
Auricularia polytricha
,
Corilopsis occidentalis
,
Daldinia concentrica
,
Daedalea elegans
and
Tricholoma lobayensis
were investigated for their antimicrobial activities using filter paper disc and hole diffusion methods. Bacteria such as
Bacillus cereus
,
Escherichia coli
,
Klebsiella pneumoniae
,
Proteus vulgaris
and
Staphylococcus aureus
were well inhibited by these mushroom extracts, while
Pseudomonas aeruginosa
was resistant to all the mushroom samples except
Tricholoma lobayensis
. The study on the antifungal effect of these mushroom extracts revealed that
Aspergillus niger
,
Aspergillus flavus
,
Candida albicans
and
Microsporum boulardii
were either weakly inhibited or not inhibited at all. The minimum inhibitory concentration (MIC) ranged between 1.25 and 9.00mg/ml for bacteria and between 10.50 and 17.50mg/ml for fungi. These results are discussed in relation to therapeutic value of the studied mushrooms.