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African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 9, No. 2, 2006, pp. 129-132
Bioline Code: md06022
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 9, No. 2, 2006, pp. 129-132

 en Short communication- Effect of Subchronic Administration of Ethanolic Stembark Extract of Mammea Africana check for this species in other resources Sabine on Haematological and Biochemical Parameters of Rats
AntiaB. S., Okokon J. E., Nwidu L. L. and Jackson C.L

Abstract

The effect of subchronic administration of ethanolic stembark extract of Mammea Africana check for this species in other resources (30 - 90mg/kg) on haematological and biochemical parameters of rats was studied. Significant decreases in activities of serum alkaline phosphatase (ALP), Aspartate aminotransferase (AST) and Alanine aminotransferase (ALT) as well as decreases in the levels of serum total protein and albumin were observed in the extract treated rats compared to control. White Blood Cell counts of the extract treated rats also decreased significantly while other haematogical parameters were unaffected. Thus, the extract has a slight toxicity at the doses studied.

Keywords
Mammea africana, alkaline phosphatase, aminotransferase, haemotology.

 
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