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African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 11, No. 1, 2008, pp. 39-46
Bioline Code: md08006
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 11, No. 1, 2008, pp. 39-46

 en Thirst Perception and Dryness of Mouth in Healthy Young Adults Nigerians
Igbokwe, V.U. & Obika, L.F.O.


This study examined the threshold for thirst perception (TP) using the visual analogue scale (VAS). Thirst perception (TP) and dryness of mouth (DM) were studied in normal subjects, (n = 137; 78 males of height, 1.72 ± 0.01, age, 23 ± 0.26, body mass index, 21.11 ± 0.29, and 59 females of height, 1.65 ± 0.01, age, 21 ± 0.23, body mass index, 21.0 ± 0.27). The results showed that (i) TP and DMin males, (1.21 ± 0.15 cm and 1.14 ± 0.16cm respectively) and in females, (1.10 ± 0.16cm and 1.04 ± 0.17cm respectively) were similar. (ii) The relationship, Thirst (cm) = 0.75 (plasma arginine vasopressin ± 1.2) exists and has a mean of not thirsty of 1.2cm at the lower end of the scale. (iii) The plasma osmolality of 281mOsm/kg cannot be the threshold for TP and the plasma osmolality of 285mOsm/kg or 284.3mOsm/kg cannot be the threshold for plasma arginine vasopressin secretion but rather the mean of the lower set point of the scales for TP and plasma arginine vasopressin [PAVP] secretion. (iv) The threshold for TP using the VAS is between 1.50 - 1.575cm markings, and plasma osmolality of 286.0 - 286.25 mOsm/kg. PAVP of 0.4 – 0.5 pmol/l being the sensitivity of the osmoregulatory unit.

Thirst perception, Dryness of mouth, plasma osmolality, osmotic threshold, Visual Analogue Scale

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