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African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 11, No. 1, 2008, pp. 105-110
Bioline Code: md08014
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 11, No. 1, 2008, pp. 105-110

 en Antimicrobial Activities of Calotropis procera check for this species in other resources on Selected Pathogenic Microorganisms
Kareem, S. O.; Akpan, I. & Ojo, O. P.

Abstract

The antimicrobial effect of ethanol, aqueous and chloroform extracts of leaf and latex of Calotropis procera check for this species in other resources on six bacteria namely, Escherichia coli check for this species in other resources , Staphylococcus aureus check for this species in other resources , Staphylococcus albus check for this species in other resources , Streptococcus pyogenes check for this species in other resources , Streptococcus pneumoniae check for this species in other resources and three fungi: Aspergillus niger check for this species in other resources , Aspergillus flavus check for this species in other resources , Microsporium boulardii check for this species in other resources and one yeast Candida albicans check for this species in other resources were determined using agar well diffusion and paper disk methods. The results revealed that ethanol was the best extractive solvent for antimicrobial properties of leaf and latex of C. procera followed in order by Chloroform and aqueous (P<0.05). The ethanolic extracts of C. procera latex gave the widest zone of inhibition (14.1mm) against E-coli using agar well diffusion while 9.0 mm was recorded for the same organism in the disc plate method.The growth of six bacterial isolates were inhibited by the three extracts except P.aeruginosa and S.pyogenes that were not inhibited by the aqueous extracts of both leaf and latex of C.procera. Similarly, the growth of four test fungi were inhibited by ethanol and chloroform extracts while the aqueous extract was the least effective on the test fungi. The best antifungal activity was recorded in ethanol extract of C. procera latex against Candida albicans. The minimum inhibitory concentration (MIC) for the ethanol extract was between 5.0 and 20.0 mg/ml for fungi. This study revealed that the C.procera latex demonstrated strong inhibitory effect on the test organisms than C.procera leaf. The results therefore established a good support for the use of C.procera in traditional medicine

Keywords
Calotropisprocera, antimicrobial, extract

 
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