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African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 11, No. 2, 2008, pp. 197-202
Bioline Code: md08026
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 11, No. 2, 2008, pp. 197-202

 en Evaluation of the Inhibitory Potentials of Eight Higher Nigerian Fungi against Pathogenic Microorganisms
Jonathan, S.G.; Kigigha, L.T. & Ohimain, E.

Abstract

Studies were carried out to determine antimicrobial potentials of crude and purified methanol extracts of some selected Nigerian mushrooms against some selected pathogenic microorganisms. The best in vitro antibacterial activity (24.0mm) was observed with the purified extract (PRE) of Polyporus giganteus check for this species in other resources against E. coli. This was followed in order by PRE of Pleurotus florida check for this species in other resources against K. pneumoniae with 22.0mm (P ≤ 0.05). Among the screened higher fungi, only the extracts of Pleurotus tuber check for this species in other resources -regium, were able to inhibit the growth of P. aeruginosa. It was also observed that antifungal activities of these mushrooms were generally low. Candida albicans check for this species in other resources were inhibited by the extracts of P. giganteus and T. robustus only while other fungi produce no zone of inhibition The observed minimum inhibitory concentration (MIC) of M. jodocodo against E. coli was 2.75mg/ml while that of T. robustus against M. bourlardii was 15.75mg/ml. The significance of these observations was discussed.

Keywords
Antimicrobial, extraction, edible fungi, disease, microorganisms

 
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