search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 11, No. 2, 2008, pp. 215-219
Bioline Code: md08029
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Biomedical Research, Vol. 11, No. 2, 2008, pp. 215-219

 en Antimicrobial Effect of Phyllanthus amarus check for this species in other resources and Parquetina nigrescens check for this species in other resources on Salmonella typhi check for this species in other resources
Oluwafemi, Flora & Debiri, Folasade

Abstract

Phyllanthus amarus check for this species in other resources and Parquetina nigrescens check for this species in other resources are economic plants grown in West Africa for antimicrobial properties. Crude aqueous (hot and cold water) and ethanolic extracts of the plants were investigated for antimicrobial activity against Salmonella typhi check for this species in other resources . The organism was collected from the University College Hospital, lbadan, Nigeria and was exposed to ten standard different antibiotics and also to crude extract of P. amarus and P. nigrescens. Agar cup diffusion method was employed fro the plants extracts while disk diffusion method for the standard antibiotics. Ethanolic extracts of P. amarus had the strongest activity against Salmonella typhi with 8.0mm zone of growth inbibition followed by hot water (4.7mm) and cold water (3.8mm). This was statistically significant at P= 0.05 when compared with hot and cold water extracts. Amongst the commercial antibioticis examined, ciprofloxacin had the highest zone of growth inhibition of 9.0mm; Oflxation (6.0mm) Amoxycillin, (4.0mm) while other antibiotics had on effect on test organism. Screening carried out on P. amarus and P. nigrescens using standard methods revealed the presence of saponins, alkaloids, tannins and cardiac glycosides. P. amarus possesses significant antimicrobial activity and confirms the justification by herbalists as extract used for treatment of typhoid fever.

Keywords
P. amarus, P. nigrescens, antimicrobial activity, standard antibiotics, typhoid fever

 
© Copyright 2008 - Ibadan Biomedical Communications Group

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2017, Site last up-dated on 16-Oct-2017.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil