The antimicrobial efficacy of extracts of
Pentaclethra macrophylla
in ethanol, methanol and water was determined against
Escherichia coli
,
Staphylococcus aureus
,
Pseudomonas aeruginosa
, Klebsiella
species,
Salmonella typhi
,
Aspergills niger
and
Candida albican
using paper disc and hole diffusion methods. The results revealed that the growths of test organisms were inhibited by extracts used. The least inhibitory zone (25.0mm) was best recorded in ethanol extract against
A. niger and
C. albicans. The minimum inhibitory concentration of the extracts ranges between 62.5-250mg/ml on the test isolates. However, the antimicrobial potency of
Pentaclethra macrophylla was more prominent against bacterial isolates than fungal isolates. These findings lend more weight to the use of
Pentaclethra macrophylla seed for therapeutic purposes.
