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African Journal of Biomedical Research
Ibadan Biomedical Communications Group
ISSN: 1119-5096
Vol. 21, No. 1, 2018, pp. 7-10
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Bioline Code: md18002
Full paper language: English
Document type: Review Article
Document available free of charge
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African Journal of Biomedical Research, Vol. 21, No. 1, 2018, pp. 7-10
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BRCA1 and BRCA2 Gene Mutations in Breast Cancer among West African Women
Zouré, A.A; Bambara, H.A; Sawadogo, A.Y; Bakri, Y & Simporé, J
Abstract
There is an increase in the prevalence of cancer in Africa, while cancer was previously related to the industrialized countries. In
fact, until today studies are scanty in all the African regions to find out more about the reality of the disease. However, in West
Africa, there are few reports on the genetic factors of breast cancer. Our review was able to establish that very few studies have
described the mutations of the BRCA1 / 2 genes in Africa. The dearth of scientific data in West Africa has impacted negatively
on prevention, sensitization and management of breast cancer. We strongly suggest studies in general cancer registries of these
countries and particularly on the genetic etiology of breast cancer
Keywords
Breast cancer; Genetic risks; BRCA1/2; West Africa
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© Copyright 2018 - African Journal of Biomedical Research
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