Croatian Medical Association - Rijeka branch
Vol. 41, No. 1, 2005, pp. 49-55
Bioline Code: me05006
Full paper language: Croatian
Document type: Research Article
Document available free of charge
Medicina, Vol. 41, No. 1, 2005, pp. 49-55
© © 2005 - Croatian Medical Association - Rijeka branch
Clinical guidelines - INTRACRANIAL ULTRASONOGRAPHY IN DIAGNOSTICS OF PERINATAL BRAIN LESIONS|
Vlatka Mejaški-Bošnjak, Vlasta Đuranović, Tomislav Gojmerac, Goran Krakar
We present an overview of intracranial ultrasonography in neonates
and infants, particularly in the diagnostics of perinatal brain haemorrhagic
and hypoxic-ischemic lesions, focal vacular lesions in preterm
and term neonates, as well as the follow up of structural reorganization.
The pathogenesis of all mentioned lesions is related to perinatal
risk factors, leading to disturbed perfusion of the brain (hypo/hyperperfusion),
precipitated by poor autoregulation of cerebral blood flow
and immaturity of cerebral vessels.
The grading system, ultrasonographic diagnostic criteria and the timing
of the diagnostics for both periventricular and hypoxic ischemic
lesions are considered.
The type, size and localisation of perinatal lesions predict the prognosis
of neurodevelopmental outcome. Peri-intraventricular haemorrhages
of lower grade have a favourable prognosis; wheras neurodevelopmental
disorders are related to a more severe grade of intraventricular
haemmorhages and hypoxic ischemic lesions. Periventricular
leukomalacia is the most common type of neurodevelopmental disorders,
whereby the cystic form is in most cases related to cerebral palsy.
Intracranial ultrasonography, perinatal brain lesion, periintraventricular hemorrhage, hypoxic-ischaemic brain lesion, prognosis of neurodevelopmental outcome
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