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Medicina
Croatian Medical Association - Rijeka branch
ISSN: 0025-7729
Vol. 44, No. 3-4, 2008, pp. 229-334
Bioline Code: me08028
Full paper language: Croatian
Document type: Review Article
Document available free of charge

Medicina, Vol. 44, No. 3-4, 2008, pp. 229-334

 hr Celijakija – pregled i predviđanja
Barbarić, Irena


Celijakija ili glutenska enteropatija je doživotno nepodnošenje glutena. Gluten je bjelančevina koja se nalazi u nekim vrstama žitarica (pšenici, raži i ječmu). U nekim područjima zahvaća 1% opće populacije, a udio dijagnosticiranih osoba ovisi najviše o dostupnosti novih dijagnostičkih seroloških testova, kao i tendencija zdravstvene službe da nespecifične i vrlo različite simptome i znakove bolesti poveže s ovom dijagnozom. U genetski predisponiranih osoba unos glutena hranom oštećuje crijevnu sluznicu, pa je upijanje hranjivih tvari otežano. Tako dolazi do pothranjenosti jer je iskorištavanje kalorijskih vrijednosti hrane nedovoljno, ali i drugih različitih stanja uzrokovanih nedovoljnim iskorištavanjem vitamina i minerala. Jedini način liječenja je doživotna prehrana bez glutena. Skrb za oboljele od celijakije zahtijeva holistički pristup koji uključuje različite zdravstvene i socijalne struke. U osoba koje se ne pridržavaju takve prehrane ili im bolest nije dijagnosticirana može doći do ozbiljnih zdravstvenih komplikacija. Osobe koje se strogo pridržavaju bezglutenske prehrane imaju isti rizik od komplikacija kao i zdrave osobe.


bezglutenska prehrana, celijakija, gluten, glutenska enteropatija

 
 en Coeliac disease – a retrospective and prospective view
Barbarić, Irena

Abstract

Coeliac disease or gluten entheropathy is the lifelong gluten intolerance. Gluten is a protein contained within some cereals (wheat, rye and barley). In some areas of the world coeliac disease affects about 1% of general population. The rate of patients recognized with celiac disease depends mostly on novel diagnostic serologic tests but also on the awareness of health care providers that unspecific and very different signs and symptoms can indicate the diagnosis of this disease. In genetically predisposed people, gluten damages the small bowel mucosa and impairs absorptive function which leads to malnutrition as a consequence of decreased calorie intake including minerals and vitamins. Currently, the only known therapy is gluten-free diet. The approach to coeliac patients must be holistic and multidisciplinary. In misrecognized patients or in patients who not follow gluten-free diet, serious complications can develop. Patients on gluten-free diet have the same complications rate as healthy people.

Keywords
coeliac disease, gluten, gluten entheropathy, gluten-free diet

 
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