search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


Medicina
Croatian Medical Association - Rijeka branch
ISSN: 0025-7729
Vol. 44, No. 3-4, 2008, pp. 235-240
Bioline Code: me08029
Full paper language: Croatian
Document type: Research Article
Document available free of charge

Medicina, Vol. 44, No. 3-4, 2008, pp. 235-240

 hr Biopsija i histomorfometrija kosti u dijagnostici osteoporoze i metaboličkih bolesti kosti
Cvek, Sanja Zoričić


Osteoporoza je sistemska bolest skeleta karakterizirana redukcijom koštane mase i poremećajem unutrašnje arhitekture koštanog tkiva, što dovodi do povećane fragilnosti kostiju i sklonosti prijelomima. Prema WHO, glavni dijagnostički kriterij za osteoporozu je BMD za lumbalni dio kralježnice i femur više od 2,5 SD ispod normalne vrijednosti koštane mase referentne za određenu starosnu dob. Statistički izvještaji govore da je danas u Hrvatskoj oko 250.000 žena oboljelo od osteoporoze. Prema službenim smjernicama za dijagnostiku, prevenciju i liječenje osteoporoze u RH, u dijagnostici osteoporoze, pored denzitometrije, rendgenograma torako-lumbalne kralježnice te laboratorijskih pokazatelja pregradnje kosti, preporučuje se i biopsija kosti s histomorfometrijom. Cilj je ovog rada uputiti na metodu koštane biopsije i histomorfometrije i njenu vrijednost


biopsija kosti, histomorfometrija, metaboličke bolesti kosti, osteoporoza

 
 en Bone biopsy and histomorphometry as a tool for diagnosis of osteoporosis and other metabolic bone diseases
Cvek, Sanja Zoričić

Abstract

Osteoporosis is systemic skeletal disease characterised by reduction of bone mass as well as disruption of internal architecture of the osseous tissue which leads to increased bone fragility and tendency for fracture. According to WHO the primary diagnostic criteria for osteoporosis is BMD more than 2,5 SD below normal values of bone mass referral for certain age, measured on lumbar spine and femoral bone. Over 250.000 women are diagnosed with osteoporosis in Croatia. According to guidance for osteoporosis diagnosis, prevention and treatment, except for bone densitometry, X-rays of thoraco-lumbar spine and biochemical markers of bone remodeling, bone biopsy and histomorphometry are suggested. The aim of this paper is to describe bone biopsy and histomorphometry as a valuable method for diagnostics and follow up in metabolic bone diseases and osteoporosis.

Keywords
bone biopsy, histomorphometry, metabolic bone disease and osteoporosis.

 
© Copyright © 2008 - Croatian Medical Association - Rijeka branch
Alternative site location: http://hrcak.srce.hr/medicina

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2019, Site last up-dated on 11-Sep-2019.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil