Plasma transfusion on the day of oocyte aspiration may reduce ovarian hyperstimulation syndrome in patients with polycystic ovary|
Yousef M. Alhelou, Tharwat Y., Alhelou, Ghada S. Alkerenawi, Sandra N. Akela,
Objective: To determine the efficiency of plasma transfusion on the day of oocyte aspiration in preventing ovarian hyperstimulation syndrome (OHSS) in polycystic ovary (PCO) patients undergoing ART cycles.
Design: Prospective randomized study.
Setting: The ART center at Alhelou International Hospital, Gaza city, Palestine.
Subjects: 93 PCO patients who are at risk of OHSS.
Intervention: 1-3 units of plasma were administrated on the day of oocyte aspiration.
Main Outcome Measures: The incidence and degrees of OHSS.
Results: 93 cases were randomized in total, 46 cases received plasma, 47 cases did not receive plasma (control). There was a noticeable difference in the two groups related to the occurrence of OHSS, the plasma group had 4 mild 8.7% and 1 moderate 2.2%, total % 10.9, where as 7 mild 14.9% and 3 moderate 6.4%, total % 21.3 in the control group, all were early onset of OHSS.
Conclusion: Our study proposes that plasma administration may reduce the percent and degree of OHSS in PCO patients undergoing ART. Plasma administration has no effect on the pregnancy rate.
OHSS, PCOS, Plasma, ART, ICSI