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Middle East Fertility Society Journal
Middle East Fertility Society
ISSN: 1110-5690
Vol. 12, No. 1, 2007, pp. 63-65
Bioline Code: mf07011
Full paper language: English
Document type: Research Article
Document available free of charge

Middle East Fertility Society Journal, Vol. 12, No. 1, 2007, pp. 63-65

 en CASE REPORT - Subfertile couples with inv (9) (p11q13): Report of two cases
Ghasemi, Nasrin; Kalantar, Seyed Mehdi; Aflatoonian, Abbas & Tayebi, Naeimeh

Abstract

This paper reports two cases of inversion chromosome 9 in one of partners from two sub fertile couples. The first case was the woman with idiopathic recurrent spontaneous abortion in the first trimester of her pregnancy, which referred to genetic counseling clinic. Cytogenetic examination showed that her karyotype was 46 XX, inv (9) (p11q13), and her husband’s karyotype was normal (46 XY). The second couple referred for idiopathic infertility to genetic counseling clinic. The woman's karyotype was normal (46XX), but she did not have any pregnancy in 5 years of marriage. Her husband's karyotype was 46XY, inv (9) (p11q13). His semen analysis showed low motility, but sperm count and morphology was normal. The abnormal karyotype of these cases, 46 XX, inv (9) (p11q13) and 46 XY, inv (9) (p11q13) could be acknowledged as a reason of infertility during evaluation of unknown infertile couple.

Keywords
Inversion chromosome 9, recurrent spontaneous abortion, idiopathic infertility

 
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