Comparison of implantation and pregnancy rate using two methods of embryo selection: "Pronuclear morphology and embryo quality" and "embryo morphology alone"|
Robab Davar; Shamsi Beigi & Mehrdad Soleimani
Objective: Despite many advances in the field of reproductive medicine, with <30% of embryos that are transferred ever resulting in clinical pregnancies. This study compared implantation and pregnancy rate in two methods of embryo selection.
Design: randomized double blind clinical trial
Materials and Methods: Research and clinical center for infertility, Yazd, Iran
Subject: In this randomized double blind clinical trial, 95 patients referring to the Yazd Research and Clinical Center for Infertility for IVF or ICSI treatment were included from March to December 2004. These patients randomly allocated in two groups. (A & B) In group A (Case), embryo selection was done by pronuclear morphology and embryo quality while in group B (Control), this process was done by embryo morphology methods alone. Oocytes were classified according to their quality. According to cause of infertility ICSI or IVF was done. Finally = 4 embryos with best quality were selected and transferred to uterus.
Main outcome measures: Implantation rate, Pregnancy Rate
Results: In case group, 419 and in control group, 444 oocytes were collected. In case group 129 embryos and in control group 151 embryos were transferred. Number and percent of clinical pregnancies was 14 (31.11%) and 9 (18%) and implantation rate was 18 (13.95%) and 12 (7.94%) in case and control groups.
Conclusion: Until to achievement of better methods and confirmation of blastocystic transferring, we can use from this method in Infertility center.
implantation, pronuclear morphology, pregnancy