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Middle East Fertility Society Journal
Middle East Fertility Society
ISSN: 1110-5690
Vol. 17, No. 1, 2012, pp. 54-56
Bioline Code: mf12010
Full paper language: English
Document type: Case Report
Document available free of charge

Middle East Fertility Society Journal, Vol. 17, No. 1, 2012, pp. 54-56

 en Amnion graft as a possible source of stem cells for endometrial regeneration after lysis of severe intrauterine adhesions
Amer, Mohamed I.; Abd-El-Maeboud, Karim & Alloub, Amal


Background:The current traditional management of severe intrauterine adhesions (IUAs) is hysteroscopic adhesiolysis with application of either an intrauterine contraceptive device or a Foley catheter balloon with reported recurrence in up to 50% of cases. Recently, significant improvement with the use of amnion graft following hysteroscopic lysis of severe IUA was reported.
Case: In the present case, endometrial stromal cells (ESCs) were found within and on the surface of amniotic membrane two months after its grafting intrauterine which was confirmed with CD10 immunohistochemistry.
Conclusion: Amniotic membrane graft after hysteroscopic lysis of severe IUA, might act as a source of stem cells for endometrial regeneration; a role that will be of great value especially in severe IUAs. Further studies to confirm this finding are warranted.

Intrauterine adhesions; Amnion graft; Stem cells

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