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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 9, No. 2, 2002, pp. 43-46
Bioline Code: mj02016
Full paper language: English
Document type: Research Article
Document available free of charge

Malaysian Journal of Medical Sciences, Vol. 9, No. 2, 2002, pp. 43-46

 en Wernicke's Encephalopthy associated with hyperemesis gravidarum - A CASE REPORT
Wahinuddin Sulaiman, Azerin Othman, Monniaty Mohamad, Hj. Rosemi Salleh, Lily Mushahar


Two cases of Wernicke's encephalopathy due to hyperemesis gravidarum are described. The first patient presented with bilateral papilloedema, altered sensorium and the second with bilateral retinal haemorrhages, ophthalmoplegia and nystagmus. Both patients were diagnosed with Wernicke's encephalopathy on clinical ground since there were no laboratory facilities to measure red cell transketolase and thiamine pyrophosphate levels. This is a rare but treatable complication of hyperemesis gravidarum (HG) and due to lack of diagnostic tools, there is often diagnostic uncertainty, delay in commencing appropriate treatment, as well as irreversible damage to the upper brain stem and death.

Wernicke's encephalopathy, hyperemesis gravidarum

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