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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 14, No. 2, 2007, pp. 54-57
Bioline Code: mj07026
Full paper language: English
Document type: Case Report
Document available free of charge

Malaysian Journal of Medical Sciences, Vol. 14, No. 2, 2007, pp. 54-57

 en Hereditary Spherocytosis in a Malay Patient with Chronic Haemolysis
Sheikh, Muhammad Kamil; Yusoff, Narazah Mohd.; Kaur, Gurjeet & Khan, Farhat Aziz


This case report describes a 35-year-old lady who presented with generalized weakness and lethargy of two weeks duration and jaundice of more than 20 years duration. Her initial workup was suggestive of haemolysis and blood film showed a leucoerythoblastic picture with moderate microspherocytes. She was finally diagnosed as a case of hereditary spherocytosis after ruling out other possible causes of chronic haemolysis and supported by an abnormal osmotic fragility test, although family members refused for screening. Hereditory spherocytosis is uncommon in Malay population and presentation with jaundice of 20 years duration with leucoerythroblastic picture on blood film were interesting features in this case. Patient is being followed closely for need of splenectomy in near future as per severity of haemolysis and currently being managed with folic acid supplement.

Hereditary spherocytosis, Jaundice, Chronic haemolysis, Leucoerythroblastic picture. Microspherocytes.

© Copyright 2007 - Malaysian Journal of Medical Science
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