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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 16, No. 1, 2009, pp. 25-33
Bioline Code: mj09004
Full paper language: English
Document type: Short Communication
Document available free of charge

Malaysian Journal of Medical Sciences, Vol. 16, No. 1, 2009, pp. 25-33

 en Radioiodine I-131 For The Therapy Of Graves’ Disease
Mumtaz, Malik; Lin, Lim Shueh; Hui, Khaw Chong & Khir, Amir Sharifuddin Mohd

Abstract

Graves’ disease is a common cause of hyperthyroidism. Treatment options for Graves’ disease include antithyroid medication, surgery or radioactive iodine (I-31) or RAI. This review will focus on the approach to RAI therapy; discussing dose selection, patient preparation, and consideration before and after administering RAI, examining aspects of pre-treatment with antithyroid medication as well as discussing possible adverse events including hypothyroidism and possible worsening of thyroidassociated opthalmopathy. Follow-up is lifelong with the aim of ensuring the patient remains euthyroid or on replacement therapy if there is evidence of hypothyroidism. While there are controversies in treatment of thyrotoxicosis with RAI, with appropriate patient selection and regular follow-up, radioiodine is a safe and effective modality in achieving high cure rates.

Keywords
radioactive iodine, Graves’ disease, thyroid, treatment, medical sciences

 
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Alternative site location: http://www.medic.usm.my/publication/mjms/

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