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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 16, No. 3, 2009, pp. 43-46
Bioline Code: mj09023
Full paper language: English
Document type: Short Communication
Document available free of charge

Malaysian Journal of Medical Sciences, Vol. 16, No. 3, 2009, pp. 43-46

 en Isosporiasis in HIV/AIDS Patients in Edo State, Nigeria
Olusegun, Akinbo Frederick; Okaka, Christopher Ehis & Machado, Ricardo Lucas


Background: The role of opportunistic infections in accelerating disease progression in HIV- positive individuals, leading to quick death, is still receiving serious attention. The objective of this study was to determine the prevalence of Isospora belli check for this species in other resources infections in HIV-positive patients in Edo State, Nigeria between August 2007 and March 2008.

Methods: A total of 268 samples from HIV-positive patients and 20 samples from HIV-negative patients were processed using the modified Ziehl-Neelsen staining technique to microscopically identify the presence of I. belli oocysts.

Results: The overall prevalence of the coccidian was 3.1%. Gender and age had no correlation with the prevalence of the parasite (P > 0.05). There was a significant relationship between isosporiasis and CD4+ T cell counts in HIV-positive patients (OR=11.388, 95% CI=2.797 - 46.371, P=0.0004).

Conclusions: Routine investigation of I. belli in HIV-positive subjects is advocated in tertiary health institutions.

Isospora belli, HIV, CD4 + T lymphocytes

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