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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 18, No. 4, 2011, pp. 88-90
Bioline Code: mj11058
Full paper language: English
Document type: Case Report
Document available free of charge

Malaysian Journal of Medical Sciences, Vol. 18, No. 4, 2011, pp. 88-90

 en Kimura’s Disease: A Rare Cause of Nephrotic Syndrome with Lymphadenopathy
Othman, Siti Kamariah; Daud, Kamaliah Mohd & Othman, Nor Hayati

Abstract

Kimura’s disease is a rare condition and typically presents as non-tender subcutaneous swellings in the head and neck region, usually in the pre-auricular and submandibular areas. It is associated with lymphadenopathy (both local and distal), marked peripheral eosinophilia, and an elevated IgE level. It can easily be mistaken for a malignant disorder. Fine needle aspiration can be misleading, and a diagnosis is established only by histopathological examination. Renal involvement, which may affect up to 60% of patients, is the only systemic manifestation. We report a case of Kimura’s disease in a Malay patient who was associated with steroid-responsive nephrotic syndrome.

Keywords
eosinophilic granuloma of soft tissue, Kimura’s disease, lymphadenopathy, neck, nephrotic syndrome

 
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Alternative site location: http://www.medic.usm.my/publication/mjms/

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