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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 20, No. 5, 2013, pp. 83-85
Bioline Code: mj13077
Full paper language: English
Document type: Case Report
Document available free of charge

Malaysian Journal of Medical Sciences, Vol. 20, No. 5, 2013, pp. 83-85

 en Pure Red Cell Aplasia Following Thymothymectomy: A Case Report
Ck Rao, Anuradha; Nayal, Bhavna & Manohar, Chethan

Abstract

Thymoma, a rare epithelial neoplasm, is the most common anterior-superior mediastinal tumour. Thymoma can occur sporadically or in association with other conditions, such as myasthenia gravis, pure red cell aplasia (PRCA), and hypogammaglobulinemia. Only 5% of thymoma cases develop PRCA; however, 10–50% of patients presenting with PRCA have an associated spindle cell type thymoma. Thymoma complicated by PRCA is associated with a poor outcome. We report the case of a 38-year-old female who presented with chest pain, and was diagnosed with an anterior mediastinal mass. A thymectomy was performed, and histopathological examination revealed mixed thymoma; two months later, the patient developed PRCA. The present case reinforces the need for clinicians to be vigilant with thymoma patients, even following thymectomy.

Keywords
erythropoiesis; mediastinum; pure red cell aplasia; thymoma

 
© Malaysian Journal of Medical Sciences
Alternative site location: http://www.medic.usm.my/publication/mjms/

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