Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
Vol. 23, No. 3, 2016, pp. 72-77
Bioline Code: mj16036
Full paper language: English
Document type: Research Article
Document available free of charge
Malaysian Journal of Medical Sciences, Vol. 23, No. 3, 2016, pp. 72-77
© Copyright 2016 - Malaysian Journal of Medical Sciences
Comparison of Dry Eye Parameters between Diabetics and Non-Diabetics in District of Kuantan, Pahang|
Aljarousha, Mohammed; Badarudin, Noor Ezailina & Che Azemin, Mohd Zulfaezal
Introduction: Diabetes may affect the human body’s systems and organs, including the eye.
Diabetic retinopathy is the 5th leading cause of blindness globally. Diabetic subjects demonstrated
dry eye symptoms that were also supported by the low values of the clinical tests.
Purpose: This study aimed to compare the dry eye symptoms and signs between diabetics
and non-diabetics and tear functions between diabetic subjects with and without dry eye.
Methods: This retrospective study was based on the observation of 643 medical files. Using a
convenience sampling method, 88 subjects were found to report diabetes mellitus. The information
extracted from the files included: date of first examination, age at first visit, gender, past ocular
history, systemic disease, symptoms of dry eye disease and details of clinical diagnostic signs. Noncontact
lens wearers were excluded. A group of 88, age and gender matched, control subjects were
included for this comparison study.
Results: The percentage of dry eye symptoms was higher in diabetic subjects (15.9%)
compared with non-diabetic subjects (13.6%; p<0.001). The percentage of dry eye symptoms was
also higher in diabetics with dry eye (63%) than in diabetics without dry eye (36.9%; p<0.001). Tear
break up time was significantly different between diabetics and non-diabetics (p<0.001) and between
diabetics with and without dry eye (p=0.046). The corneal staining was significantly different
between diabetic subjects with and without dry eye (p=0.028).
Conclusion: Dry eye symptoms were significantly associated with diabetics. Tear break up
time was significantly shorter in diabetics with dry eye compared to diabetics without dry eye.
Diabetes mellitus; dry eye syndromes; cornea; tears; signs and symptoms
Alternative site location: http://www.medic.usm.my/publication/mjms/