Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
Vol. 23, No. 6, 2016, pp. 52-59
Bioline Code: mj16079
Full paper language: English
Document type: Research Article
Document available free of charge
Malaysian Journal of Medical Sciences, Vol. 23, No. 6, 2016, pp. 52-59
© Copyright 2016 - Penerbit Universiti Sains Malaysia
Correlation of Demographic and Clinical Characteristics with Rheumatoid Factor Seropositivity in Rheumatoid Arthritis Patients|
Othman, Maizatul Akmal; Wan Ghazali, Wan Syamimee; Yahya, Nurul Khaiza & Wong, Kah Keng
Background: The rheumatoid factor (RF) blood test is the most commonly adopted test
for the diagnosis of rheumatoid arthritis (RA). RA patients who are seropositive for RF might face
a greater likelihood of developing more aggressive symptoms.
Methods: Our goal was to study the demographic and clinical characteristics, as well as
their correlation with RF seropositivity, among a series of 80 RA patients aged ≥ 18 years who
attend Hospital Universiti Sains Malaysia (HUSM).
Results: Of the 80 RA patients included in this study, 66 (82.5%) were female and 14
(17.5%) were male. No significant associations between RF seropositivity and demographic and/or clinical characteristics or other laboratory investigations were observed, including gender,
morning stiffness, individual joint involvement (from multiple sites of the body), and erythrocyte
sedimentation rate (ESR) measurement. However, a significant association between RF
seropositivity and patients aged ≥ 50 was found (P = 0.032).
Conclusion: RF seropositivity was found to be more common in much older RA patients.
autoimmune disease; rheumatoid arthritis; rheumatoid factor; erythrocyte sedimentation rate
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