search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


Malawi Medical Journal
College of Medicine, University of Malawi and Medical Association of Malawi
ISSN: 1995-7262
Vol. 24, No. 2, 2012, pp. 25-28
Bioline Code: mm12008
Full paper language: English
Document type: Research Article
Document available free of charge

Malawi Medical Journal, Vol. 24, No. 2, 2012, pp. 25-28

 en CD4 testing at clinics to assess eligibility for Antiretroviral therapy
Lumala, Rumours; van den Akker, Thomas; Metcalf, Carol Ann; Diggle, Emma; Zamadenga, Bote; Mbewa, Kingsley & Akkeson, Ann

Abstract

Background
In 2011, the Ministry of Health raised the CD4 threshold for antiretroviral therapy (ART) eligibility from <250 cells/μl and <350 cells/μl, but at the same time only 8.8% of facilities in Malawi with HIV services provided CD4 testing. We conducted a record review at 10 rural clinics in Thyolo District to assess the impact of introducing CD4 testing on identifying patients eligible for ART.
Methods:
We abstracted CD4 counts of all ART-naïve, HIV-infected patients with WHO clinical stages 1 and 2 and an initial CD4 test between May 2008 and June 2009. At four clinics, we also abstracted CD4 counts of patients not initially eligible for ART who were retested before April 2010.
Results
Of 1,113 patients tested, the initial CD4 was “≤250 cells/μl” and “≤350 cells/μl” in 534 (48.0%). Of 203 patients with follow-up results, the most recent CD4 was ≤250 cells/μl in 34 (24.5%), and ≤350 cells/μl in 64 (46.0%).
Conclusions
CD4 testing in rural clinics is feasible and identifies many patients eligible for ART who would not be identified without CD4 testing. CD4 testing needs to be scaled-up to identify patients eligible for ART. ART services need to be scaled-up concurrently to meet the resulting increased demand.

 
© Copyright 2012 - Malawi Medical Journal
Alternative site location: http://revista.uft.edu.br/index.php/jbb/index

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2017, Site last up-dated on 16-Oct-2017.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil