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Malawi Medical Journal
College of Medicine, University of Malawi and Medical Association of Malawi
ISSN: 1995-7262
Vol. 29, No. 3, 2017, pp. 265-267
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Bioline Code: mm17054
Full paper language: English
Document type: Case Report
Document available free of charge
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Malawi Medical Journal, Vol. 29, No. 3, 2017, pp. 265-267
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A 42-year-old woman with subacute reversible dementia: A cautionary tale
Kamtchum-Tatuene, Joseph; Kamwezi, Richard; Nyalubwe, Thokozani; Banda, Josephine P.; Mwangalika, Gloria; Matandika, Ian; Hemmila, Ulla; Tisell, Magnus; Koponen, Susanna; Benjamin, Laura A. & Kamalo, Patrick
Abstract
A 42-year-old woman presented with a 6-month history of diffuse headache of moderate intensity and gradual onset of generalized
weakness, imbalance, apathy, memory decline, hypophonia, dysphagia, constipation and urinary incontinence. Clinical examination
revealed several elements of a frontal lobe dysfunction including apathy with motor impersistence, presence of primitive reflexes,
generalized hyperreflexia with bilateral Hoffman sign and ankle clonus. The biological workup was unremarkable and a brain
computed tomography scan identified a giant olfactory groove meningioma. A prompt neurosurgical intervention helped to reverse
the symptoms. This case illustrates the benefits of actively looking for treatable conditions in young patients presenting with acute or
subacute dementia and emphasizes the pivotal role of early brain imaging.
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