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Malawi Medical Journal
College of Medicine, University of Malawi and Medical Association of Malawi
ISSN: 1995-7262
Vol. 30, No. 4, 2018, pp. 291-295
Bioline Code: mm18056
Full paper language: English
Document type: Review Article
Document available free of charge

Malawi Medical Journal, Vol. 30, No. 4, 2018, pp. 291-295

 en The role of cardiac magnetic resonance (CMR) in the diagnosis of cardiomyopathy: A systematic review
Mayala, Henry Anselmo; Bakari, Khamis Hassan & Wang, Zhaohui


Myocardial pathologies are significant causes of morbidity and mortality in patients worldwide. Ischemic and non-ischemic cardiomyopathies have become a worldwide epidemic of the 21st century with an increasing impact on health care systems. The 2012 European Society of Cardiology and 2013 American College of Cardiology Foundation/American Heart Association guidelines provide current therapy guidance to reduce mortality and morbidity.
This was a systematic review involving cardiac magnetic resonance (CMR) studies for the diagnosis of cardiomyopathy from January 2013 to April 2017. Out of 62 reviewed studies, only 12 were included in our study.
The average sensitivity and specificity of CMR in the diagnosis of cardiomyopathy was 86.75% (95% confidence interval [CI], 70.30% to 92.58%) and 81.75% (95% CI, 73.0% to 87.6%), respectively, and the positive predictive and negative predictive values were 80.17% and 86.75%, respectively.
Despite some limitations, our study shows that CMR has high sensitivity, specificity, and positive predictive value in diagnosing different types of cardiomyopathy. CMR may be used to differentiate types of cardiomyopathy, accurately quantify the chamber dimensions, volumes, and cardiac function, which make it useful for prognosis as well.

Cardiac magnetic resonance; dilated cardiomyopathy; hypertrophic cardiomyopathy; ischemic cardiomyopathy; late gadolinium enhancement

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