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Malawi Medical Journal
College of Medicine, University of Malawi and Medical Association of Malawi
ISSN: 1995-7262
Vol. 30, No. 4, 2018, pp. 298-301
Bioline Code: mm18058
Full paper language: English
Document type: Case Report
Document available free of charge

Malawi Medical Journal, Vol. 30, No. 4, 2018, pp. 298-301

 en A case of acute megakaryoblastic leukaemia (FAB M7), a rare type of acute myeloid leukemia (AML), in a teenager
Olatunji, Philip O; Ojo, Omotola T; Bello, Fatai O; Bakare, Binta Y & Olatunj, Ayodeji O


Acute Megakaryoblastic Leukaemia (AML, M7) is a rare type of acute myeloid leukemia (AML) evolving from primitive megakaryoblasts. It accounted for 1.2% of newly diagnosed AML according to Eastern Cooperative Oncology Group (ECOG) trials between 1984 and 1997. Patients may present with a broad variety of symptoms including low-grade fever, easy bruising, and life-threatening conditions. We report a rare case of AML, M7 in a 19-year-old lady who presented with weakness and fatigue. She was diagnosed as a case of AML, M7 on the basis of peripheral blood finding, bone marrow examination report, radiological findings and immunophenotyping.

acute myeloid leukemia; acute megakaryocytic leukaemia; immunophenotyping; myelosclerosis

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