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A case of acute megakaryoblastic leukaemia (FAB M7), a rare type of acute myeloid leukemia (AML), in a teenager
Olatunji, Philip O; Ojo, Omotola T; Bello, Fatai O; Bakare, Binta Y & Olatunj, Ayodeji O
Abstract
Acute Megakaryoblastic Leukaemia (AML, M7) is a rare type of acute myeloid leukemia (AML) evolving from primitive megakaryoblasts.
It accounted for 1.2% of newly diagnosed AML according to Eastern Cooperative Oncology Group (ECOG) trials between 1984 and
1997. Patients may present with a broad variety of symptoms including low-grade fever, easy bruising, and life-threatening conditions.
We report a rare case of AML, M7 in a 19-year-old lady who presented with weakness and fatigue. She was diagnosed as a case of AML,
M7 on the basis of peripheral blood finding, bone marrow examination report, radiological findings and immunophenotyping.
Keywords
acute myeloid leukemia; acute megakaryocytic leukaemia; immunophenotyping; myelosclerosis
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