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Indian Journal of Medical Sciences
Medknow Publications on behalf of Indian Journal of Medical Sciences Trust
ISSN: 0019-5359
EISSN: 0019-5359
Vol. 62, No. 2, 2008, pp. 35-44
Bioline Code: ms08007
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Medical Sciences, Vol. 62, No. 2, 2008, pp. 35-44

 en Life time risk for development of ten major cancers in India and its trends over the years 1982 to 2000
Satyanarayana, L. & Asthana, Smita

Abstract


Background : Understanding cancer magnitude, risk and trends will be of help in cancer control programs.
Aim : To study trends in cumulative risk up to 64 years of age as lifetime risk of developing major cancers in India during the years 1982 to 2000.
Design : Retrospective.
Setting : Secondary sources of cancer-registration data.
Materials and Methods : Data on age-specific cancer-incidence rates were collected for patients 0-64 years of age of either sex for 10 major cancer sites from the National Cancer Registry Program (NCRP) reports of India from Mumbai, Chennai, Bangalore, Bhopal and Delhi; and Barshi registries for the years 1982 or 1988 to 2000.
Statistical Analysis : Cumulative risks computed for lifetime development of cancer. Linear trends were studied using simple linear regressions.
Results : The lifetime risk among females for the10 cancer sites ranged from 0.02 to 3.3% and from 0.04 to 2.4% for the years 1982 and 2000 respectively; whereas among males, it ranged from 0.04 to 0.89% and from 0.05 to 0.95% respectively. Significant (P < 0.05) increasing trends were observed for breast, non-Hodgkin′s lymphoma (NHL), gallbladder, thyroid and ovary cancers among females; while declining trends were observed for cervix, mouth, stomach, esophagus and tongue cancers. Among males, significant (P < 0.05) increasing trends were observed for NHL and prostate cancer; whereas declining trends were observed for stomach, liver, hypopharynx and tongue cancers. Cancers of mouth and esophagus showed increasing trends (P < 0.05) in some regions and declining trends (P < 0.05) in some other.
Conclusion : Significant and higher rates of positive trends in lifetime cancer risks for breast cancer among females and for NHL among both sexes were observed.

Keywords
Cancer registry, cancer trends, cumulative risk, India, lifetime risk

 
© Copyright 2008 Indian Journal of Medical Sciences.
Alternative site location: http://www.indianjmedsci.org/

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