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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 50, No. 1, 2002, pp. 106-107
Bioline Code: ni02030
Full paper language: English
Document type: Research Article
Document available free of charge

Neurology India, Vol. 50, No. 1, 2002, pp. 106-107

 en Preliminary Observations on Valproate and Cystic Ovaries : Letter to Editor
A. Chakravarty


Women with epilepsy continue to pose special therapeutic problems and dilemmas to their physicians. The latest is the scare about development of polycystic ovarian disease (PCOD) with valproate.1 The clinical features of PCOD include oligoamenorrhea, infertility, centripetal obesity, hirsutism and raised plasma testosterone level along with bilateral ovarian enlargement and multiple cysts. Recent reports suggested on increased incidence of PCOD amongst women on valproate for epilepsy.2-9 The author's personal experience with this condition and a critical analysis of the problems at hand is presented.

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