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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 50, No. 4, 2002, pp. 473-475
Bioline Code: ni02126
Full paper language: English
Document type: Research Article
Document available free of charge

Neurology India, Vol. 50, No. 4, 2002, pp. 473-475

 en Case Report - Lithium - Induced Tardive Dystonia Treated with Clozapine
S. Chakrabarti, P.K. Chand


Tardive dystonia is an uncommon form of chronic dystonia, which usually develops on exposure to neuroleptics. Tardive dystonia (Tdt) following lithium therapy has not been previously reported. The case of 38 year old man with bipolar affective disorder who developed tardive dystonia while on maintenance lithium treatment is described. Presentation of Tdt in this patient was fairly characteristic although there was no suggestion of recent neuroleptic exposure. Tdt known to have poor treatment response, responded very well to clozapine, a novel anti-psychotic, in this case. To conclude, Tdt may develop on exposure to drugs other than neuroleptics. An adequate trial to clozapine can prove to be a useful treatment option.

Tardive dystonia, Lithium induced, Response to clozapine

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