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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 50, No. 4, 2002, pp. 518-519
Bioline Code: ni02140
Full paper language: English
Document type: Research Article
Document available free of charge

Neurology India, Vol. 50, No. 4, 2002, pp. 518-519

 en Short Report - Evaluation of Enzymes in Serum and Cerebrospinal Fluid in Cases of Stroke
N. Parakh, H.L. Gupta, A. Jain


Levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH) and creatine kinase (CK) were estimated in serum and cerebrospinal fluid of 25 patients of stroke, and were correlated with severity of disease. 21 (84%) patients had ischemic stroke and four (16%) had hemorrhagic stroke. Serum and CSF AST levels were significantly elevated in the study group. The rise in CSF AST was more in the hemorrhagic subtype than in the ischemic subtype. Serum ALT and CSF LDH levels were also significantly elevated in patients with ischemic stroke. None of the enzyme levels were related to the severity of disease as assessed by the Glasgow coma scale.

Cerebrovascular accident, Serum enzyme, CSF enzyme.

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