Letter to Editor - Craniopharyngioma in an 82-year-old male

An 82-year-old male presented with behavioral abnormalities of 6 months and loss of memory of 3 months. There was no history of urinary incontinence, headache, loss of consciousness, seizures or visual difficulties. On examination he showed signs of frontal lobe dysfunction with normal fundi. Rest of the neurological examination was unremarkable. CT scan of the brain revealed a non-enhancing hypodense nodular mass in the suprasellar area in the midline, extending towards the left side (Figure 1). A right frontal craniotomy was done and through subfrontal approach, a radical tumor resection was carried out. The lesion was partly cystic, containing machine oil-like thick fluid. Histopathological examination of the specimen was consistent with a craniopharyngioma. It revealed cystic spaces lined by flattened to stratified epithelium and peripheral pallisading of nuclei. Calcification, areas of extensive fibrosis and xanthomatous changes were also seen at places. Focal areas showed ghost appearing squamous cells (Figure 2).