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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 51, No. 2, 2003, pp. 203-205
Bioline Code: ni03063
Full paper language: English
Document type: Research Article
Document available free of charge

Neurology India, Vol. 51, No. 2, 2003, pp. 203-205

 en Ventilatory management of respiratory failure in patients with severe Guillain-Barré syndrome
A. N. Aggarwal, D. Gupta, V., Lal, D. Behera, S. K. Jindal, S. Prabhakar


Guillain-Barré syndrome (GBS) is the commonest peripheral neuropathy causing ventilatory failure, and 10-30% patients may require respiratory support. Records of 11 adult patients of GBS in respiratory failure, admitted to the Respiratory Intensive Care Unit (RICU) of our institute for mechanical ventilation over a four-year period, were studied. Six patients received intravenous immunoglobulin. The median duration of mechanical ventilation was 38 days. Seven patients underwent tracheostomy. Four patients were ventilated for less than 2 weeks and 3 for more than 2 months each. Seven developed ventilator-associated pneumonia and/or sepsis. Three patients died in, and two shortly after discharge from RICU; all had systemic problems or complications of hospitalization.

Acute inflammatory demyelinating polyneuropathy, Ventilatory failure, Mechanical ventilation, Ventilator-associated pneumonia, Sepsis, Hospital mortality.

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