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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 57, No. 3, 2009, pp. 282-286
Bioline Code: ni09083
Full paper language: English
Document type: Research Article
Document available free of charge

Neurology India, Vol. 57, No. 3, 2009, pp. 282-286

 en "Finger drop sign" in Guillain-Barrι syndrome
George, Arun; Abdurehiman, P & James, Jose


Background: Guillain-Barrι syndrome (GBS) is an acute neurological illness affecting the peripheral nervous system causing significant morbidity. The syndrome has been classified electrophysiologically into demyelinating and axonal forms. The clinical features of the axonal variant (acute motor axonal neuropathy-AMAN) are not well characterized, particularly in the Indian context. Objective: To assess the incidence, clinical presentation and disease course of patients with AMAN. Materials and Methods: This is an observational study done at a tertiary referral center in South India. The study period extended from January 2006 to July 2007. All patients with a clinical diagnosis of GBS and satisfying the electrophysiological criteria for AMAN were included. Results: There were 12 cases of AMAN out of a total of 84 cases of GBS. All AMAN patients showed a characteristic pattern of hand weakness predominant weakness of finger extensors with relatively normal power in finger flexors, wrist flexors and extensors. Proximal limb weakness was mild and was present in 85% cases. One patient had cranial nerve palsy and one had hyperreflexia. None of the patients progressed to respiratory failure. Conclusion: AMAN is a distinct subgroup in GBS showing certain distinguishing features, the most notable being predominant weakness of finger extensors.

AMAN, finger drop, Guillain-Barrι syndrome, hypereflexia, paucity of cranial nerve palsy

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