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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 57, No. 3, 2009, pp. 313-319
Bioline Code: ni09091
Full paper language: English
Document type: Report
Document available free of charge

Neurology India, Vol. 57, No. 3, 2009, pp. 313-319

 en Intra-arterial thrombolysis in basilar artery occlusions combination of intra-arterial thrombolytics and Gp IIb/IIIa inhibitors in basilar artery thrombosis
Gaikwad, S.B.; Padma, M.V.; Moses, E.J.; Sethi, Kanika; Tripathi, M.; Bhatia, R.; Prasad, K. & Mishra, N.K.


Basilar artery thrombosis has high morbidity and mortality. Though intra-arterial thrombolytics have proven efficacy in the treatment of acute basilar artery occlusion, the elevation of procoagulant factors in the blood after intra-arterial thrombolysis could result in subsequent thrombus formation and clinical deterioration. Glycoprotein IIb/IIIa inhibitors have been shown to reduce this elevation in procoagulants. We present a pilot study of three cases of acute basilar artery occlusion treated with a combination of intra-arterial thrombolytics and Gp IIb/IIIa inhibitor with remarkable clinical recovery seen in all the patients.

Basilar artery thrombosis, glycoprotein IIb/IIIa inhibitor, intra-arterial thrombolysis

© Copyright 2009 Neurology India.
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