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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886
EISSN: 0028-3886
Vol. 58, No. 5, 2010, pp. 747-751
Bioline Code: ni10204
Full paper language: English
Document type: Report
Document available free of charge

Neurology India, Vol. 58, No. 5, 2010, pp. 747-751

 en Tubular aggregate myopathy: A phenotypic spectrum and morphological study
Ghosh, Amrita; Narayanappa, Gayathri; Taly, Arun B.; Chickbasavaiya, Yasha T.; Mahadevan, Anita; Vani, Santosh; Atchayaram, Nalini; Mohapatra, Ishani & Susarala, Krishna Shankar

Abstract

Tubular aggregates (TAs) are inclusions described in skeletal muscle in a variety of disorders. In a retrospective analysis, TAs were found in 18 (0.24%) cases and involved a spectrum of clinical phenotypes. Ultrastructurally, four distinct types of aggregates were noted. There was no correlation between the clinical phenotypes, duration of illness and types of TAs.

Keywords
Cramps, familial dementia, limb girdle myasthenia, lower motor neuron syndrome, myalgia, noncompressive myelopathy, periodic paralysis, tubular aggregates, ultrastructure

 
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